Description

2-(4-Methylpiperazinomethyl)-4'-Trifluoromethylbenzophenone is a high-purity, advanced pharmaceutical intermediate characterized by its unique benzophenone core functionalized with a methylpiperazine and a trifluoromethyl group. This compound matters for its critical role in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring targeted molecular scaffolds. Pharmaceutical R&D and fine chemical synthesis companies need this precise building block to develop next-generation drugs, leveraging its structural complexity for creating compounds with potential enhanced bioavailability and metabolic stability.

Application

• Key Intermediate in Pharmaceutical Synthesis: Serves as a crucial precursor in the multi-step synthesis of complex drug candidates, especially in central nervous system (CNS) and oncology research.
• Building Block for Kinase Inhibitors: Used in the development of protein kinase inhibitors, where the trifluoromethyl and piperazine motifs are valuable for potency and selectivity.
• Research & Development (R&D): Employed in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization processes.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke molecules under cGMP conditions.
• Chemical Biology Probes: Utilized in the creation of chemical probes for studying biological pathways and target validation.

Basic Information

Product Name	2-(4-Methylpiperazinomethyl)-4'-Trifluoromethylbenzophenone
CAS No.	898762-15-7
Molecular Formula	C20H21F3N2O
Molecular Weight	362.39 g/mol
Synonyms	4'-(Trifluoromethyl)-2-[(4-methyl-1-piperazinyl)methyl]benzophenone; 2-[(4-Methylpiperazin-1-yl)methyl]-4'-(trifluoromethyl)benzophenone; 2-(4-Methyl-1-piperazinylmethyl)-4'-trifluoromethylbenzophenone; 898762-15-7; Benzophenone, 2-[(4-methyl-1-piperazinyl)methyl]-4'-(trifluoromethyl)-; 4'-Trifluoromethyl-2-(4-methylpiperazinomethyl)benzophenone
EINECS	Contact for details

Quality Control

Our 2-(4-Methylpiperazinomethyl)-4'-Trifluoromethylbenzophenone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with ICH guidelines, supporting its use in regulated pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, open flame, and incompatible materials. The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.