Description

2-Chloro-3'-[8-(1,4-Dioxa-8-Azaspiro[4.5]Decyl)Methyl]-4-Fluorobenzophenone is a sophisticated organic intermediate featuring a benzophenone core functionalized with halogen and spirocyclic protecting groups. This compound matters for its role as a key building block in the synthesis of complex molecules, particularly in pharmaceutical research and development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced material sectors for constructing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and other therapeutic agents.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides, leveraging its halogenated benzophenone structure.
• Material Science: Serves as a monomer or cross-linking agent in the development of specialty polymers and advanced organic materials.
• Chemical Biology & Proteomics: Employed as a photoaffinity labeling probe or a scaffold for designing enzyme inhibitors and molecular probes.
• Academic & Contract Research: Utilized in university and CRO laboratories for methodological development and exploratory synthesis projects.
• Scale-up & Process Chemistry: Acts as a defined intermediate for optimizing synthetic routes and scaling up production of target molecules.

Basic Information

Item	Detail
Product Name	2-Chloro-3'-[8-(1,4-Dioxa-8-Azaspiro[4.5]Decyl)Methyl]-4-Fluorobenzophenone
CAS No.	898762-11-3
Molecular Formula	C23H25ClFNO3
Molecular Weight	417.90 g/mol
Synonyms	4-Fluoro-2-chloro-3'-[8-(1,4-dioxa-8-azaspiro[4.5]dec-8-yl)methyl]benzophenone; 2-Chloro-4-fluoro-3'-[8-(1,4-dioxa-8-azaspiro[4.5]decyl)methyl]benzophenone; 2-Chloro-3'-(1,4-dioxa-8-azaspiro[4.5]dec-8-ylmethyl)-4-fluorobenzophenone; Benzophenone, 2-chloro-3'-[8-(1,4-dioxa-8-azaspiro[4.5]dec-8-yl)methyl]-4-fluoro-; 898762-11-3; CAS 898762-11-3
EINECS	Contact for details

Quality Control

Our 2-Chloro-3'-[8-(1,4-Dioxa-8-Azaspiro[4.5]Decyl)Methyl]-4-Fluorobenzophenone is produced under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports compliance with cGMP and ISO standards for research and development use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.