Description

4'-Bromo-3-[8-(1,4-Dioxa-8-Azaspiro[4.5]Decyl)Methyl]Benzophenone is a sophisticated organic building block featuring a benzophenone core functionalized with a bromo group and a protected amino spirocycle. This compound matters as a key intermediate in advanced pharmaceutical synthesis, particularly for the development of active pharmaceutical ingredients (APIs) and complex bioactive molecules. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for constructing novel molecular architectures.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of complex drug candidates, especially those targeting neurological and metabolic disorders.
• Agrochemical Research: Used in the development of novel pesticides and herbicides, leveraging its unique halogenated and heterocyclic structure.
• Chemical Biology Probe Synthesis: Serves as a scaffold for creating molecular probes to study protein-ligand interactions and enzyme functions.
• Material Science Research: Potential monomer or additive in the development of specialty polymers with specific optical or electronic properties.
• Academic & Institutional R&D: Employed in university and research institute laboratories for methodological studies in organic synthesis and catalysis.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific projects requiring this precise molecular framework.

Basic Information

Product Name	4'-Bromo-3-[8-(1,4-Dioxa-8-Azaspiro[4.5]Decyl)Methyl]Benzophenone
CAS No.	898761-71-2
Molecular Formula	C21H22BrNO3
Molecular Weight	416.31 g/mol
Synonyms	4'-Bromo-3-[(8-(1,4-dioxa-8-azaspiro[4.5]decyl))methyl]benzophenone; 3-[(1,4-Dioxa-8-azaspiro[4.5]dec-8-yl)methyl]-4'-bromobenzophenone; 898761-71-2; Benzophenone, 4'-bromo-3-[8-(1,4-dioxa-8-azaspiro[4.5]decanyl)methyl]-; 4'-Bromo-3-((1,4-dioxa-8-azaspiro[4.5]dec-8-yl)methyl)benzophenone; 4'-Bromo-3-[(1,4-dioxa-8-azaspiro[4.5]dec-8-yl)methyl]benzophenone
EINECS	Contact for details

Quality Control

Our 4'-Bromo-3-[8-(1,4-Dioxa-8-Azaspiro[4.5]Decyl)Methyl]Benzophenone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most demanding synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere such as nitrogen or argon when not in use to prevent degradation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.