Description

3'-[8-(1,4-Dioxa-8-Azaspiro[4.5]Decyl)Methyl]-2-Methyl Benzophenone is a high-purity, advanced pharmaceutical intermediate featuring a complex spirocyclic structure. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and other therapeutic areas. It is essential for research institutions, contract development and manufacturing organizations (CDMOs), and pharmaceutical companies engaged in process development and scale-up of new drug candidates.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the multi-step production of proprietary drug substances.
• Research & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and the discovery of new chemical entities.
• Process Chemistry: Serves as a defined intermediate in the optimization and scaling of API manufacturing routes.
• Reference Standard: Employed as an analytical standard for quality control and method validation during API production.
• Custom Synthesis: A starting point for the custom synthesis of more complex, target-specific molecules for client projects.

Basic Information

Product Name	3'-[8-(1,4-Dioxa-8-Azaspiro[4.5]Decyl)Methyl]-2-Methyl Benzophenone
CAS No.	898761-29-0
Molecular Formula	C22H25NO3
Molecular Weight	351.44 g/mol
Synonyms	2-Methyl-3'-[8-(1,4-dioxa-8-azaspiro[4.5]decan-8-yl)methyl]benzophenone; 2-Methyl-3'-(1,4-dioxa-8-azaspiro[4.5]decan-8-ylmethyl)benzophenone; 3'-(1,4-Dioxa-8-azaspiro[4.5]decan-8-ylmethyl)-2-methylbenzophenone; 898761-29-0; Benzophenone, 3'-[8-(1,4-dioxa-8-azaspiro[4.5]decyl)methyl]-2-methyl-
EINECS	Contact for details

Quality Control

Our 3'-[8-(1,4-Dioxa-8-Azaspiro[4.5]Decyl)Methyl]-2-Methyl Benzophenone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, open flames, and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.