Description

4-Chloro-4'-(1,3-Dioxolan-2-Yl)-2-Fluorobenzophenone is a high-value, multi-functional organic intermediate characterized by its benzophenone core substituted with chloro, fluoro, and protected carbonyl (dioxolane) groups. This compound matters for its role as a critical building block in the synthesis of complex molecules, offering precise reactivity for constructing advanced chemical architectures. It is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for creating novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders or metabolic diseases.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and insecticides, leveraging its halogenated structure for bioactivity.
• Material Science Research: Serves as a monomer or cross-linking agent in the development of specialty polymers and advanced organic electronic materials.
• Ligand and Catalyst Development: Employed in organic chemistry research to create novel ligands for transition metal catalysis or organocatalysts.
• Chemical Biology Probes: Utilized as a scaffold for developing molecular probes and fluorescent tags used in biochemical and cellular assays.

Basic Information

Product Name	4-Chloro-4'-(1,3-Dioxolan-2-Yl)-2-Fluorobenzophenone
CAS No.	898760-64-0
Molecular Formula	C₁₆H₁₂ClFO₃
Molecular Weight	306.72 g/mol
Synonyms	2-Fluoro-4-chloro-4'-(1,3-dioxolan-2-yl)benzophenone; 4-Chloro-2-fluoro-4'-(1,3-dioxolan-2-yl)benzophenone; 4-Chloro-4'-(1,3-dioxolan-2-yl)-2-fluorobenzophenone; 2-Fluoro-4-chloro-4'-(2,2-dimethyl-1,3-dioxolan-4-yl)benzophenone (related protected form); Benzophenone, 4-chloro-4'-(1,3-dioxolan-2-yl)-2-fluoro-; 898760-64-0; 4'-Chloro-2-fluoro-4-(1,3-dioxolan-2-yl)benzophenone
EINECS	Contact for details

Quality Control

Our 4-Chloro-4'-(1,3-Dioxolan-2-Yl)-2-Fluorobenzophenone is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports applications requiring high-purity intermediates for research and regulated synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥97.0% (Area %)
Related Substances (HPLC)	Total impurities ≤3.0% Any single impurity ≤1.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.