Description

2-Chloro-4'-(1,3-Dioxolan-2-Yl)-4-Fluorobenzophenone is a high-purity, synthetically valuable organic intermediate characterized by its benzophenone core functionalized with chloro, fluoro, and a protected carbonyl group. This compound matters for its role as a critical building block in the synthesis of complex molecules, particularly in advanced pharmaceutical research and development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, leveraging its halogenated benzophenone structure.
• Material Science Research: Serves as a monomer or functional component in the development of advanced polymers and organic electronic materials.
• Chemical Biology & Proteomics: Employed as a photoaffinity labeling agent or a scaffold for designing molecular probes due to the benzophenone moiety.
• Academic & Contract Research: Utilized in university and CRO laboratories for methodological development and exploratory synthetic chemistry.
• Custom Synthesis & Scale-Up: A starting material for contract manufacturing organizations (CMOs) engaged in custom synthesis projects from gram to kilogram scale.

Basic Information

Item	Details
Product Name	2-Chloro-4'-(1,3-Dioxolan-2-Yl)-4-Fluorobenzophenone
CAS No.	898760-60-6
Molecular Formula	C₁₆H₁₂ClFO₃
Molecular Weight	306.72 g/mol
Synonyms	2-Chloro-4'-(1,3-dioxolan-2-yl)-4-fluorobenzophenone; 4-Fluoro-2-chloro-4'-(1,3-dioxolan-2-yl)benzophenone; 2-Chloro-4-fluoro-4'-(1,3-dioxolan-2-yl)benzophenone; Benzophenone, 2-chloro-4'-(1,3-dioxolan-2-yl)-4-fluoro-; (2-Chlorophenyl)[4-fluoro-4'-(1,3-dioxolan-2-yl)phenyl]methanone
EINECS	Contact for details

Quality Control

Our 2-Chloro-4'-(1,3-Dioxolan-2-Yl)-4-Fluorobenzophenone is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting all critical parameters are provided and available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases. The compound is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.