Description

4'-(1,3-Dioxolan-2-Yl)-3-Trifluoromethylbenzophenone is a specialized organic intermediate featuring a benzophenone core substituted with a trifluoromethyl group and a protected aldehyde functionality. This compound matters for its role as a key building block in the synthesis of complex molecules, particularly in the pharmaceutical and agrochemical sectors. It is primarily needed by R&D chemists and process development scientists working on active pharmaceutical ingredients (APIs), advanced materials, and novel crop protection agents.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of drug candidates, especially those targeting central nervous system (CNS) disorders, inflammation, and metabolic diseases.
• Agrochemical Synthesis: Serves as a building block for developing advanced herbicides, fungicides, and insecticides with enhanced efficacy and environmental profiles.
• Material Science Research: Used in the development of specialty polymers, liquid crystals, and organic electronic materials due to its aromatic and fluorinated structure.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes and inhibitors for studying enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific projects requiring high-purity, complex intermediates.

Basic Information

Product Name	4'-(1,3-Dioxolan-2-Yl)-3-Trifluoromethylbenzophenone
CAS No.	898760-52-6
Molecular Formula	C17H13F3O3
Molecular Weight	322.28 g/mol
Synonyms	3-Trifluoromethyl-4'-(1,3-dioxolan-2-yl)benzophenone; 2-[4-(Benzoyl)-2-(trifluoromethyl)phenyl]-1,3-dioxolane; 4'-(1,3-Dioxolan-2-yl)-3-(trifluoromethyl)benzophenone; [4-(1,3-Dioxolan-2-yl)phenyl][3-(trifluoromethyl)phenyl]methanone; Benzophenone, 4'-(1,3-dioxolan-2-yl)-3-(trifluoromethyl)-
EINECS	Contact for details

Quality Control

Our 4'-(1,3-Dioxolan-2-Yl)-3-Trifluoromethylbenzophenone is produced under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to quality supports applications requiring high-purity intermediates under cGMP or ISO 9001 frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.