Description

4'-(1,3-Dioxolan-2-Yl)-2-Trifluoromethylbenzophenone CAS NO 898760-49-1 is a high-value, specialized benzophenone derivative characterized by its trifluoromethyl and dioxolane functional groups. This compound serves as a critical advanced pharmaceutical intermediate and a versatile building block in modern organic synthesis. It is primarily sought after by R&D and production teams in the pharmaceutical, agrochemical, and advanced materials sectors for the development of novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders, inflammation, and metabolic diseases.
• Agrochemical Synthesis: Used in the research and development of new-generation herbicides and fungicides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Organic Light-Emitting Diodes (OLEDs): Acts as a building block for electron-transport materials or host materials in OLED devices due to its conjugated benzophenone core.
• Ligand and Catalyst Development: Employed in organometallic chemistry to create novel ligands for catalysis, leveraging the ketone and dioxolane functionalities for metal coordination.
• Fluorinated Polymer Research: Serves as a monomer or modifier in the synthesis of specialty fluorinated polymers with unique surface properties and chemical resistance.
• Academic and Industrial R&D: A valuable reagent for methodological studies in organic chemistry, including cross-coupling reactions and fluorination chemistry.

Basic Information

Item	Details
Product Name	4'-(1,3-Dioxolan-2-Yl)-2-Trifluoromethylbenzophenone
CAS No.	898760-49-1
Molecular Formula	C17H13F3O3
Molecular Weight	322.28 g/mol
Synonyms	2-Trifluoromethyl-4'-(1,3-dioxolan-2-yl)benzophenone; 4'-(1,3-Dioxolan-2-yl)-2-(trifluoromethyl)benzophenone; [4-(1,3-Dioxolan-2-yl)phenyl][2-(trifluoromethyl)phenyl]methanone; 2-(Trifluoromethyl)-4'-(1,3-dioxolan-2-yl)benzophenone; Benzophenone, 4'-(1,3-dioxolan-2-yl)-2-(trifluoromethyl)-; 898760-49-1; 4'-(2,2-Dimethyl-1,3-dioxolan-4-yl)-2-(trifluoromethyl)benzophenone (related protected form)
EINECS	Contact for details

Quality Control

Our production of 4'-(1,3-Dioxolan-2-Yl)-2-Trifluoromethylbenzophenone adheres to a stringent quality management system. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR, IR, and MS. We provide a detailed Certificate of Analysis (COA) with each shipment, ensuring traceability and compliance with your research or cGMP-grade requirements. Specifications can be customized to meet specific project needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to minimize exposure to moisture. This material should be stored separately from strong bases and fluorides.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.