Description

4'-(1,3-Dioxolan-2-Yl)-2-Fluorobenzophenone is a specialized fluorinated benzophenone derivative, serving as a crucial synthetic intermediate in advanced organic chemistry. Its value lies in its unique molecular architecture, which incorporates both a fluorinated aromatic ring and a protected carbonyl group, enabling precise chemical transformations. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs) and complex organic materials.

Application

• Pharmaceutical Intermediate: A key building block in the multi-step synthesis of complex drug candidates, particularly those requiring fluorinated aromatic systems.
• Agrochemical Research: Used in the development of new herbicides, pesticides, and fungicides where the fluorobenzophenone core contributes to biological activity and stability.
• Material Science: Serves as a precursor for advanced polymers, liquid crystals, or organic electronic materials due to its rigid, conjugated structure.
• Chemical Synthesis: Acts as a versatile electrophile or protected aldehyde equivalent in complex organic reactions, including cross-coupling and nucleophilic addition.
• Academic & R&D Laboratories: Employed in methodological studies and the discovery of new synthetic pathways in organic and medicinal chemistry.

Basic Information

Product Name	4'-(1,3-Dioxolan-2-Yl)-2-Fluorobenzophenone
CAS No.	898760-46-8
Molecular Formula	C₁₆H₁₃FO₃
Molecular Weight	272.27 g/mol
Synonyms	2-Fluoro-4'-(1,3-dioxolan-2-yl)benzophenone; 2-Fluoro-4'-(1,3-dioxolan-2-yl)benzophenone; 4'-(1,3-Dioxolan-2-yl)-2-fluorobenzophenone; 2-Fluoro-4'-(2,2-dimethyl-1,3-dioxolan-4-yl)benzophenone (related protected form); Benzophenone, 2-fluoro-4'-(1,3-dioxolan-2-yl)-; (2-Fluorophenyl)[4-(1,3-dioxolan-2-yl)phenyl]methanone
EINECS	Contact for details

Quality Control

Our production of 4'-(1,3-Dioxolan-2-Yl)-2-Fluorobenzophenone adheres to stringent internal quality protocols to ensure batch-to-batch consistency and high purity. While typically supplied as a research-grade material, specifications can be tailored to meet project-specific requirements, including higher purity grades for critical applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (typically 15-25°C). Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.