Description

4'-(1,3-Dioxolan-2-Yl)-3-Fluorobenzophenone is a high-purity fluorinated benzophenone derivative featuring a protected carbonyl group. This compound is a critical advanced pharmaceutical intermediate (API intermediate) valued for its role in constructing complex molecular architectures. It is primarily utilized by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and inflammatory diseases.
• Agrochemical Synthesis: Used in research and development for creating new generation herbicides and fungicides with enhanced efficacy.
• Organic Light-Emitting Diode (OLED) Materials: Serves as a precursor in the development of electron-transport or host materials for advanced display technologies.
• Liquid Crystal & Polymer Chemistry: Employed as a monomer or additive to impart specific fluorinated properties to advanced polymers and liquid crystal mixtures.
• Academic & Contract Research: A valuable reagent for methodological studies in organic synthesis, including cross-coupling and fluorination chemistry.
• Chemical Reference Standard: Used for analytical method development, validation, and quality control in regulatory and industrial laboratories.

Basic Information

Product Name	4'-(1,3-Dioxolan-2-Yl)-3-Fluorobenzophenone
CAS No.	898760-12-8
Molecular Formula	C₁₆H₁₃FO₃
Molecular Weight	272.27 g/mol
Synonyms	3-Fluoro-4'-(1,3-dioxolan-2-yl)benzophenone; 2-[4-(Benzoyl)-2-fluorophenyl]-1,3-dioxolane; 4'-(1,3-Dioxolan-2-yl)-3-fluorobenzophenone; (3-Fluoro-4-(1,3-dioxolan-2-yl)phenyl)(phenyl)methanone; Benzophenone, 4'-(1,3-dioxolan-2-yl)-3-fluoro-; 898760-12-8; 4-(1,3-Dioxolan-2-yl)-3'-fluorobenzophenone
EINECS	Contact for details

Quality Control

Our 4'-(1,3-Dioxolan-2-Yl)-3-Fluorobenzophenone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and KF titration for moisture content, to ensure it meets the stringent requirements for pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound is moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.