Description

Cyclobutyl 3-(1,3-Dioxolan-2-Yl)Phenyl Ketone is a specialized organic compound featuring a ketone functional group linked to a cyclobutyl moiety and a phenyl ring substituted with a 1,3-dioxolane protecting group. This unique molecular architecture makes it a valuable advanced pharmaceutical intermediate (API intermediate) and a versatile building block in synthetic organic chemistry. It is primarily utilized by research institutions and industrial manufacturers engaged in the development and production of novel active pharmaceutical ingredients (APIs), agrochemicals, and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the multi-step synthesis of complex drug molecules, particularly those targeting central nervous system (CNS) disorders or requiring specific stereochemistry.
• Agrochemical Synthesis: Used as a building block for creating novel herbicides, fungicides, or insecticides with enhanced efficacy and selectivity.
• Organic Synthesis Research: Acts as a versatile synthon in academic and industrial R&D for constructing complex heterocyclic compounds and exploring new chemical reactions.
• Material Science: Potential intermediate in the synthesis of specialty polymers, liquid crystals, or organic electronic materials due to its rigid and functionalized structure.
• Process Chemistry Development: Employed in scaling up synthetic routes from laboratory to pilot plant and commercial production, where consistent quality is critical.

Basic Information

Product Name	Cyclobutyl 3-(1,3-Dioxolan-2-Yl)Phenyl Ketone
CAS No.	898759-74-5
Molecular Formula	C15H18O3
Molecular Weight	246.30 g/mol
Synonyms	3-(1,3-Dioxolan-2-yl)phenyl cyclobutyl ketone; Cyclobutyl[3-(1,3-dioxolan-2-yl)phenyl]methanone; 1-[3-(1,3-Dioxolan-2-yl)phenyl]cyclobutan-1-one; 3-(1,3-Dioxolan-2-yl)benzoic acid cyclobutyl ester (common misnomer); Ketone, cyclobutyl 3-(1,3-dioxolan-2-yl)phenyl-; CAS 898759-74-5
EINECS	Contact for details

Quality Control

Our Cyclobutyl 3-(1,3-Dioxolan-2-Yl)Phenyl Ketone is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, which includes data from techniques such as HPLC, GC, NMR, and mass spectrometry. Our quality commitment supports compliance with cGMP standards for pharmaceutical intermediates and ISO guidelines for industrial applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Water Content (KF)	≤ 0.5% w/w

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.