Description

3,5-Difluoro-3'-(1,3-Dioxolan-2-Yl)Benzophenone is a high-purity, advanced pharmaceutical intermediate characterized by its unique benzophenone core functionalized with fluorine and a protected aldehyde group. This compound is critical for its role as a key building block in the synthesis of complex active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders and other therapeutic areas. It is primarily utilized by research institutions, custom synthesis houses, and large-scale pharmaceutical manufacturers engaged in innovative drug development programs.

Application

• Pharmaceutical Intermediate: A crucial precursor in the multi-step synthesis of novel drug candidates, especially in medicinal chemistry research.
• Active Pharmaceutical Ingredient (API) Synthesis: Serves as a key building block for constructing complex molecular architectures found in target APIs.
• Organic Light-Emitting Diode (OLED) Materials Research: Used in the development of electron-transport or host materials due to its fluorinated benzophenone structure.
• Liquid Crystal and Advanced Polymer Synthesis: Acts as a monomer or functionalizing agent for creating materials with specific optical and electronic properties.
• Agrochemical Intermediate: Employed in the research and development of new generation herbicides and pesticides.
• Academic and Industrial R&D: A valuable reagent for methodological studies in organic synthesis, including cross-coupling and fluorination chemistry.

Basic Information

Product Name	3,5-Difluoro-3'-(1,3-Dioxolan-2-Yl)Benzophenone
CAS No.	898759-68-7
Molecular Formula	C₁₆H₁₂F₂O₃
Molecular Weight	290.26 g/mol
Synonyms	3,5-Difluoro-3'-(1,3-dioxolan-2-yl)benzophenone; [3-(1,3-Dioxolan-2-yl)phenyl](3,5-difluorophenyl)methanone; 3,5-Difluoro-3'-(1,3-dioxolan-2-yl)benzophenone; Methanone, [3-(1,3-dioxolan-2-yl)phenyl](3,5-difluorophenyl)-; Benzophenone, 3,5-difluoro-3'-(1,3-dioxolan-2-yl)-
EINECS	Contact for details

Quality Control

Our 3,5-Difluoro-3'-(1,3-Dioxolan-2-Yl)Benzophenone is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound should be kept under an inert atmosphere for long-term storage to maximize stability. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.