Description

4-(1,3-Dioxolan-2-Ylmethyl)-1-Ethoxybenzene is a specialized aromatic ether compound featuring a dioxolane-protected aldehyde or ketone functional group. This molecular architecture makes it a valuable protected intermediate in multi-step organic synthesis, particularly for the pharmaceutical and agrochemical industries. It is primarily sought by R&D chemists and process development scientists for constructing complex molecules where selective deprotection is required.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), especially for molecules requiring the controlled introduction of benzaldehyde or acetophenone derivatives.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides where the ethoxybenzene moiety is a critical structural component.
• Fine Chemical Production: Serves as a precursor for dyes, pigments, and other performance chemicals requiring specific aromatic ether linkages.
• Academic & Industrial Research: A valuable reagent for methodological development in organic chemistry, including studies on protecting group strategies and cross-coupling reactions.
• Material Science: Potential monomer or modifier in the development of specialized polymers and liquid crystals.

Basic Information

Product Name	4-(1,3-Dioxolan-2-Ylmethyl)-1-Ethoxybenzene
CAS No.	898759-48-3
Molecular Formula	C12H16O3
Molecular Weight	208.25 g/mol
Synonyms	1-Ethoxy-4-[(1,3-dioxolan-2-yl)methyl]benzene; 4-[(1,3-Dioxolan-2-yl)methyl]-1-ethoxybenzene; 2-[(4-Ethoxyphenyl)methyl]-1,3-dioxolane; p-Ethoxybenzaldehyde dioxolane acetal; (4-Ethoxybenzylidene) acetaldehyde cyclic acetal; 1,3-Dioxolane, 2-[(4-ethoxyphenyl)methyl]-; Benzene, 1-ethoxy-4-[(1,3-dioxolan-2-yl)methyl]-
EINECS	Contact for details

Quality Control

We maintain a rigorous quality management system to ensure batch-to-batch consistency and high purity. Our products undergo comprehensive analytical testing, including HPLC, GC, and NMR, to verify identity and purity. A Certificate of Analysis (COA) detailing all specifications is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider under an inert atmosphere to preserve stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.