Description

2-Chloro-3'-(1,3-Dioxolan-2-Yl)-4-Fluorobenzophenone is a high-purity, advanced pharmaceutical intermediate characterized by its unique halogenated benzophenone structure. This compound is critical for the synthesis of complex active pharmaceutical ingredients (APIs), offering a versatile building block for medicinal chemistry research and development. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the production of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the multi-step synthesis of complex drug candidates, particularly those targeting central nervous system (CNS) disorders.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• API Synthesis: Used in the controlled construction of specific molecular architectures required for final Active Pharmaceutical Ingredients.
• Chemical Reference Standard: Employed as an analytical standard for quality control and method development in pharmaceutical analysis.
• Organic Synthesis Building Block: Utilized in academic and industrial research for developing new synthetic methodologies involving halogenated ketones and protected aldehydes.

Basic Information

Product Name	2-Chloro-3'-(1,3-Dioxolan-2-Yl)-4-Fluorobenzophenone
CAS No.	898759-40-5
Molecular Formula	C₁₆H₁₂ClFO₃
Molecular Weight	306.72 g/mol
Synonyms	2-Chloro-3'-(1,3-dioxolan-2-yl)-4-fluorobenzophenone; 4-Fluoro-2-chloro-3'-(1,3-dioxolan-2-yl)benzophenone; 2-Chloro-4-fluoro-3'-(1,3-dioxolan-2-yl)benzophenone; Benzophenone, 2-chloro-3'-(1,3-dioxolan-2-yl)-4-fluoro-; 898759-40-5; (2-Chlorophenyl)[3-(1,3-dioxolan-2-yl)-4-fluorophenyl]methanone
EINECS	Contact for details

Quality Control

Our 2-Chloro-3'-(1,3-Dioxolan-2-Yl)-4-Fluorobenzophenone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for research and development use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep the container tightly sealed to protect from moisture. Store away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.