Description

3-Chloro-3'-(1,3-Dioxolan-2-Yl)-4-Fluorobenzophenone is a high-purity, advanced pharmaceutical intermediate characterized by its distinct benzophenone core functionalized with chloro, fluoro, and protected carbonyl groups. This compound is of critical importance for its role in the synthesis of complex active pharmaceutical ingredients (APIs), where its specific substitution pattern enables precise molecular construction. It is primarily needed by research institutions and manufacturers in the pharmaceutical and agrochemical sectors engaged in developing new therapeutic agents and specialty chemicals.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and anti-inflammatory research.
• Agrochemical Synthesis: Used in the development of advanced herbicides and pesticides, leveraging its halogenated aromatic structure.
• Organic Light-Emitting Diode (OLED) Materials: Serves as a precursor for electron-transport or host materials in electronic applications.
• Liquid Crystal & Polymer Chemistry: Acts as a monomer or cross-linking agent for creating specialized polymers with specific optical properties.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological development and discovery chemistry.
• Fine Chemical Production: Integral to multi-step synthetic routes for other high-value, complex organic molecules.

Basic Information

Product Name	3-Chloro-3'-(1,3-Dioxolan-2-Yl)-4-Fluorobenzophenone
CAS No.	898759-22-3
Molecular Formula	C₁₆H₁₂ClFO₃
Molecular Weight	306.72 g/mol
Synonyms	3-Chloro-3'-(1,3-dioxolan-2-yl)-4'-fluorobenzophenone; 4-Fluoro-3'-(1,3-dioxolan-2-yl)-3-chlorobenzophenone; 2-[3-Chloro-4-fluorophenyl][3-(1,3-dioxolan-2-yl)phenyl]methanone; Benzophenone, 3-chloro-3'-(1,3-dioxolan-2-yl)-4-fluoro-; 898759-22-3; 3'-Chloro-3-(1,3-dioxolan-2-yl)-4-fluorobenzophenone
EINECS	Contact for details

Quality Control

Our 3-Chloro-3'-(1,3-Dioxolan-2-Yl)-4-Fluorobenzophenone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting full specifications are provided with every shipment. We adhere to cGMP principles where applicable to support our clients' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.