Description

2-(3,4,5-Trifluorobenzoyl)Pyridine is a high-purity fluorinated aromatic ketone building block, essential for advanced organic synthesis. Its unique trifluoromethyl-substituted benzoyl pyridine structure makes it a critical intermediate for developing novel active pharmaceutical ingredients (APIs) and agrochemicals. This compound is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecules with enhanced biological activity and metabolic stability.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in kinase inhibitor and CNS-active molecule research.
• Agrochemical Synthesis: Used in the development of next-generation herbicides and fungicides, where the fluorine atoms improve lipophilicity and target binding.
• Ligand & Catalyst Development: Serves as a precursor for creating specialized ligands in transition metal catalysis and organocatalysis.
• Material Science Research: Employed in the synthesis of fluorinated organic semiconductors and liquid crystals for electronic applications.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis houses serving the life sciences sector.
• Academic & Institutional Research: Used in university and government labs for methodological studies in fluorination chemistry and heterocycle synthesis.

Basic Information

Product Name	2-(3,4,5-Trifluorobenzoyl)Pyridine
CAS No.	898758-18-4
Molecular Formula	C12H6F3NO
Molecular Weight	237.18 g/mol
Synonyms	2-(3,4,5-Trifluorobenzoyl)pyridine; Pyridine, 2-(3,4,5-trifluorobenzoyl)-; 3,4,5-Trifluoro-2-pyridinyl phenyl ketone; (3,4,5-Trifluorophenyl)(pyridin-2-yl)methanone; 2-Pyridyl 3,4,5-trifluorophenyl ketone; 898758-18-4; (Pyridin-2-yl)(3,4,5-trifluorophenyl)methanone
EINECS	Contact for details

Quality Control

Our 2-(3,4,5-Trifluorobenzoyl)Pyridine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with customer specifications. Our quality commitment supports applications requiring GMP-grade intermediates and materials for regulatory filings.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.