Description

3-(1,3-Dioxan-2-Yl)-2'-[(4-Trifluoromethyl)Phenyl]Propiophenone is a specialized organic intermediate featuring a dioxane-protected carbonyl group and a trifluoromethylphenyl moiety. This compound is valued for its role as a key building block in the synthesis of complex molecules, particularly in pharmaceutical research and development. It is primarily sought by fine chemical manufacturers and R&D laboratories engaged in creating novel active pharmaceutical ingredients (APIs) and advanced materials.

Application

• Pharmaceutical Intermediate: A crucial precursor in the multi-step synthesis of target drug candidates, especially those requiring the introduction of a trifluoromethyl group for enhanced metabolic stability and bioavailability.
• Agrochemical Research: Used in developing advanced pesticides and herbicides, where the trifluoromethyl group can improve compound activity and environmental profile.
• Material Science: Serves as a monomer or functional additive in the research of specialty polymers and liquid crystals.
• Organic Synthesis: Employed in academic and industrial laboratories for constructing complex molecular architectures, leveraging its protected carbonyl functionality for selective reactions.
• Fluorine Chemistry: Acts as a valuable substrate for studying and developing new fluorination and functionalization methodologies.

Basic Information

Product Name	3-(1,3-Dioxan-2-Yl)-2'-[(4-Trifluoromethyl)Phenyl]Propiophenone
CAS No.	898757-56-7
Molecular Formula	C20H19F3O3
Molecular Weight	364.36 g/mol
Synonyms	2'-[(4-Trifluoromethyl)Phenyl]-3-(1,3-Dioxan-2-Yl)Propiophenone; 1-[2-(1,3-Dioxan-2-yl)-1-oxo-3-phenylpropyl]-4-(trifluoromethyl)benzene; 3-(1,3-Dioxan-2-yl)-1-[4-(trifluoromethyl)phenyl]-1-propanone; 898757-56-7; Propiophenone, 3-(1,3-dioxan-2-yl)-2'-[(4-(trifluoromethyl)phenyl]-
EINECS	Contact for details

Quality Control

Our 3-(1,3-Dioxan-2-Yl)-2'-[(4-Trifluoromethyl)Phenyl]Propiophenone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay and impurity profiles. Our quality commitment aligns with cGMP standards for pharmaceutical intermediates, ensuring reliability for your critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.