Description

2'-Chloro-4',5'-Difluoro-4-(5,5-Dimethyl-1,3-Dioxan-2-Yl)Butyrophenone is a high-purity, advanced pharmaceutical intermediate characterized by its unique halogenated and protected ketone structure. This compound is critical for the synthesis of complex active pharmaceutical ingredients (APIs), particularly in the development of new therapeutic agents. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the discovery and production of novel fluorinated drug candidates.

Application

• Key Intermediate in API Synthesis: Serves as a crucial building block in multi-step synthetic routes for novel fluorinated pharmaceuticals.
• Pharmaceutical Research & Development: Used in medicinal chemistry for the design and optimization of new drug molecules with enhanced biological activity.
• Precursor for Fluorinated Compounds: The difluoro and chloro substituents make it a valuable precursor for introducing specific halogenated motifs into target molecules.
• Agrochemical Intermediate: Potential application in the synthesis of advanced, high-performance agrochemicals and pesticides.
• Material Science Research: May be investigated for the synthesis of specialty chemicals or functional materials requiring specific fluorinated aromatic components.

Basic Information

Product Name	2'-Chloro-4',5'-Difluoro-4-(5,5-Dimethyl-1,3-Dioxan-2-Yl)Butyrophenone
CAS No.	898757-32-9
Molecular Formula	C₁₆H₁₉ClF₂O₃
Molecular Weight	332.77 g/mol
Synonyms	2'-Chloro-4',5'-difluoro-4-(5,5-dimethyl-1,3-dioxan-2-yl)butyrophenone; 4-(5,5-Dimethyl-1,3-dioxan-2-yl)-2'-chloro-4',5'-difluorobutyrophenone; 898757-32-9; Butyrophenone, 2'-chloro-4',5'-difluoro-4-(5,5-dimethyl-1,3-dioxan-2-yl)-; 2-Chloro-4,5-difluoro-4'-(5,5-dimethyl-1,3-dioxan-2-yl)butyrophenone
EINECS	Contact for details

Quality Control

Our 2'-Chloro-4',5'-Difluoro-4-(5,5-Dimethyl-1,3-Dioxan-2-Yl)Butyrophenone is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistent quality suitable for pharmaceutical R&D. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.