Description

3-(1,3-Dioxan-2-Yl)-3'-Iodo-4'-Methylpropiophenone is a specialized iodinated aromatic ketone derivative featuring a dioxane-protecting group, making it a valuable synthetic intermediate. This compound matters for its role in facilitating complex organic transformations, particularly in the construction of advanced pharmaceutical scaffolds and functional materials. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for use in cross-coupling reactions and as a precursor for further functionalization.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), especially those requiring iodinated aromatic motifs.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and plant growth regulators.
• Material Science: Serves as a precursor for organic electronic materials, such as organic light-emitting diodes (OLEDs) and semiconductors.
• Cross-Coupling Reactions: An essential substrate in palladium-catalyzed reactions like Suzuki, Stille, and Negishi couplings for carbon-carbon bond formation.
• Chemical Synthesis: Utilized in academic and industrial R&D for exploring new synthetic methodologies and creating complex molecular architectures.
• Ligand and Catalyst Development: Acts as a starting material for synthesizing specialized ligands and organocatalysts.

Basic Information

Product Name	3-(1,3-Dioxan-2-Yl)-3'-Iodo-4'-Methylpropiophenone
CAS No.	898757-13-6
Molecular Formula	C14H17IO3
Molecular Weight	360.19 g/mol
Synonyms	3'-Iodo-4'-methyl-3-(1,3-dioxan-2-yl)propiophenone; 1-[3-Iodo-4-methylphenyl]-3-(1,3-dioxan-2-yl)propan-1-one; 3-(1,3-Dioxan-2-yl)-1-(3-iodo-4-methylphenyl)propan-1-one; 898757-13-6; 3-(1,3-Dioxan-2-yl)-3'-iodo-4'-methylpropiophenone; Propiophenone, 3-(1,3-dioxan-2-yl)-3'-iodo-4'-methyl-
EINECS	Contact for details

Quality Control

Our 3-(1,3-Dioxan-2-Yl)-3'-Iodo-4'-Methylpropiophenone undergoes rigorous quality testing to ensure compliance with industry standards. We employ advanced analytical techniques including HPLC, GC, NMR, and mass spectrometry to verify identity, purity, and consistency. Certificates of Analysis (COA) detailing batch-specific results are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling should be performed under appropriate conditions to minimize degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.