Description

4'-Azetidinomethyl-3,4-Dichlorobenzophenone is a high-purity, advanced pharmaceutical intermediate characterized by its unique azetidine and benzophenone structure. This compound is critical for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring complex molecular architectures. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of new chemical entities and process optimization.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of proprietary drug candidates, especially those targeting central nervous system (CNS) disorders.
• Organic Synthesis Research: Used in academic and industrial R&D for constructing complex heterocyclic compounds and exploring new reaction pathways.
• Process Chemistry Development: Serves as a critical starting material or intermediate for scaling up API manufacturing processes under GMP conditions.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.
• Reference Standard: High-purity grades are used as analytical standards for method development and quality control in API production.

Basic Information

Product Name	4'-Azetidinomethyl-3,4-Dichlorobenzophenone
CAS No.	898757-00-1
Molecular Formula	C17H15Cl2NO
Molecular Weight	320.21 g/mol
Synonyms	3,4-Dichloro-4'-(azetidin-1-ylmethyl)benzophenone; 1-[(4-Benzoyl-2,5-dichlorophenyl)methyl]azetidine; 4'-(Azetidin-1-ylmethyl)-3,4-dichlorobenzophenone; (3,4-Dichlorophenyl)[4-(azetidin-1-ylmethyl)phenyl]methanone; Azetidine, 1-[[4-(3,4-dichlorobenzoyl)phenyl]methyl]-; 898757-00-1; 4'-Azetidin-1-ylmethyl-3,4-dichlorobenzophenone
EINECS	Contact for details

Quality Control

Our 4'-Azetidinomethyl-3,4-Dichlorobenzophenone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the stringent requirements for pharmaceutical R&D and production. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, and we support custom purity specifications to meet specific project needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Individual impurity ≤ 0.5%
Total Impurities	≤ 2.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.