Description

4-Azetidinomethyl-4'-Trifluoromethylbenzophenone is a high-purity, advanced pharmaceutical intermediate featuring a unique azetidine moiety. This compound is critical for medicinal chemistry research and development, particularly in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers focused on developing new therapeutic agents.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders and anti-inflammatory pathways.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization due to its azetidine and trifluoromethyl functional groups.
• Protease Inhibitor Development: Serves as a precursor in the development of enzyme inhibitors, leveraging the benzophenone scaffold.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for client-specific synthetic routes.
• Chemical Biology Probes: Useful in the development of molecular probes for studying biological targets and mechanisms.
• Academic Research: Utilized in university and institutional labs for exploratory organic synthesis and new methodology development.

Basic Information

Item	Details
Product Name	4-Azetidinomethyl-4'-Trifluoromethylbenzophenone
CAS No.	898756-86-0
Molecular Formula	C18H16F3NO2
Molecular Weight	335.32 g/mol
Synonyms	4-(Azetidin-1-ylmethyl)-4'-(trifluoromethyl)benzophenone; 1-[(4-Benzoyl-3-(trifluoromethyl)phenyl)methyl]azetidine; 4'-Trifluoromethyl-4-azetidinomethylbenzophenone; (4-(Azetidin-1-ylmethyl)phenyl)(4-(trifluoromethyl)phenyl)methanone; Azetidine, 1-[[4-[4-(trifluoromethyl)benzoyl]phenyl]methyl]-; CAS 898756-86-0
EINECS	Contact for details

Quality Control

Our 4-Azetidinomethyl-4'-Trifluoromethylbenzophenone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to ensure traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). The product should be kept under an inert atmosphere if long-term storage is required to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.