Description

4'-Azetidinomethyl-3-Trifluoromethylbenzophenone is a high-purity, advanced pharmaceutical intermediate characterized by its unique benzophenone core functionalized with an azetidine and a trifluoromethyl group. This compound matters for its critical role in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting central nervous system (CNS) disorders and other therapeutic areas. Research and development teams in the global pharmaceutical and biotechnology sectors need this precise chemical building block to accelerate drug discovery and process development.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly for CNS-targeted therapies.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization due to its unique azetidine and trifluoromethyl motifs.
• Process Chemistry Development: Serves as a critical starting material or intermediate in scaling up API synthesis under GMP conditions.
• Bioconjugation & Probe Synthesis: Potential use in creating chemical probes for biochemical assays and target identification.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of specialized, high-value compounds for clinical trials.

Basic Information

Product Name	4'-Azetidinomethyl-3-Trifluoromethylbenzophenone
CAS No.	898756-84-8
Molecular Formula	C18H16F3NO
Molecular Weight	319.32 g/mol
Synonyms	3-Trifluoromethyl-4'-(azetidin-1-ylmethyl)benzophenone; [4-(Azetidin-1-ylmethyl)phenyl][3-(trifluoromethyl)phenyl]methanone; 1-({4-[3-(Trifluoromethyl)benzoyl]benzyl})azetidine; 4'-(Azetidin-1-ylmethyl)-3'-(trifluoromethyl)benzophenone
EINECS	Contact for details

Quality Control

Our 4'-Azetidinomethyl-3-Trifluoromethylbenzophenone is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development applications. Each lot undergoes comprehensive analytical characterization, including HPLC for purity, NMR for structural confirmation, and MS for identity verification. A Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The product is moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.