Description

2,4-Difluoro-2'-[8-(1,4-Dioxa-8-Azaspiro[4.5]Decyl)Methyl]Benzophenone is a sophisticated organic intermediate featuring a benzophenone core functionalized with fluorine atoms and a protected spirocyclic amine moiety. This compound is valued for its role as a key building block in the synthesis of complex molecules, particularly in pharmaceutical research and development. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced material science sectors for constructing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of active pharmaceutical ingredients (APIs), especially those targeting central nervous system (CNS) disorders or requiring fluorinated motifs for enhanced metabolic stability.
• Agrochemical Research: Used in the development of new-generation herbicides, fungicides, or pesticides, where the difluorobenzophenone structure can contribute to biological activity.
• Ligand and Catalyst Development: The spirocyclic amine group makes it a valuable scaffold for creating novel ligands used in asymmetric catalysis or metal-organic frameworks (MOFs).
• Material Science Precursor: Acts as a monomer or functionalizing agent in the production of specialty polymers, dyes, or photoactive materials.
• Chemical Biology Probe Synthesis: Utilized to create fluorescent tags or molecular probes for studying biological processes, leveraging its benzophenone photochemistry.
• Academic & Contract Research: Employed in university and CRO (Contract Research Organization) laboratories for methodological studies and the discovery of new chemical entities.

Basic Information

Product Name	2,4-Difluoro-2'-[8-(1,4-Dioxa-8-Azaspiro[4.5]Decyl)Methyl]Benzophenone
CAS No.	898756-63-3
Molecular Formula	C24H25F2NO3
Molecular Weight	413.46 g/mol
Synonyms	2,4-Difluoro-2'-[8-(1,4-dioxa-8-azaspiro[4.5]dec-8-yl)methyl]benzophenone; 2'-(8-(1,4-Dioxa-8-azaspiro[4.5]dec-8-yl)methyl)-2,4-difluorobenzophenone; Benzophenone, 2,4-difluoro-2'-[8-(1,4-dioxa-8-azaspiro[4.5]dec-8-yl)methyl]-; 898756-63-3; 2,4-Difluoro-2'-(1,4-dioxa-8-azaspiro[4.5]dec-8-ylmethyl)benzophenone
EINECS	Contact for details

Quality Control

Our production of 2,4-Difluoro-2'-[8-(1,4-Dioxa-8-Azaspiro[4.5]Decyl)Methyl]Benzophenone adheres to stringent quality management systems. Every batch undergoes comprehensive analytical characterization to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing specifications such as assay (HPLC), related substances, and physical properties are provided and available upon request. We support cGMP compliance for pharmaceutical applications and can tailor quality protocols to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.