Description

4-Bromo-2'-[8-(1,4-Dioxa-8-Azaspiro[4.5]Decyl)Methyl]-2-Fluorobenzophenone is a sophisticated fluorinated benzophenone derivative that serves as a critical pharmaceutical intermediate and advanced organic building block. Its unique spirocyclic and halogenated structure makes it invaluable for constructing complex molecules in medicinal chemistry. This high-purity compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical sectors, particularly for developing new active ingredients.

Application

• Key Intermediate in Pharmaceutical Synthesis: Primarily used in the research and development of novel drug candidates, especially in central nervous system (CNS) and oncology therapeutic areas.
• Building Block for Agrochemicals: Employed in the synthesis of advanced pesticides and herbicides, leveraging its fluorinated aromatic system.
• Material Science Research: Acts as a precursor for specialty polymers and advanced organic materials requiring specific photochemical or electronic properties.
• Ligand and Catalyst Development: Used in organometallic chemistry to create novel ligands for catalytic processes.
• Academic and R&D Laboratories: Serves as a standard or starting material for methodological studies in organic synthesis and fluorine chemistry.
• Custom Synthesis and Contract Manufacturing: A vital component for companies offering bespoke chemical synthesis services for complex, low-volume specialty chemicals.

Basic Information

Item	Details
Product Name	4-Bromo-2'-[8-(1,4-Dioxa-8-Azaspiro[4.5]Decyl)Methyl]-2-Fluorobenzophenone
CAS No.	898756-36-0
Molecular Formula	C21H21BrFNO3
Molecular Weight	434.30 g/mol
Synonyms	4-Bromo-2'-[8-(1,4-dioxa-8-azaspiro[4.5]decan-8-yl)methyl]-2-fluorobenzophenone; 2-Fluoro-4-bromo-2'-(1,4-dioxa-8-azaspiro[4.5]decan-8-ylmethyl)benzophenone; 4-Bromo-2'-(1,4-dioxa-8-azaspiro[4.5]decan-8-ylmethyl)-2-fluorobenzophenone; Benzophenone, 4-bromo-2'-[8-(1,4-dioxa-8-azaspiro[4.5]decyl)methyl]-2-fluoro-; Fluorinated Spirocyclic Benzophenone Intermediate; 898756-36-0 (CAS Registry Number)
EINECS	Contact for details

Quality Control

Our production of 4-Bromo-2'-[8-(1,4-Dioxa-8-Azaspiro[4.5]Decyl)Methyl]-2-Fluorobenzophenone adheres to stringent quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and available upon request, supporting compliance in regulated GMP and research environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.