Description

4-Chloro-2'-[8-(1,4-Dioxa-8-Azaspiro[4.5]Decyl)Methyl]-3-Fluorobenzophenone CAS NO 898756-19-9 is a sophisticated, high-purity organic intermediate featuring a benzophenone core with chloro and fluoro substituents, integrated with a 1,4-dioxa-8-azaspiro[4.5]decane moiety. This compound is critical for its role as a key building block in the synthesis of complex, biologically active molecules, offering precise structural control for advanced research and development. It is primarily sought after by pharmaceutical and agrochemical R&D laboratories for the development of new active ingredients, including potential kinase inhibitors and other therapeutic agents.

Application

• Pharmaceutical Intermediate: A crucial precursor in the multi-step synthesis of novel drug candidates, particularly in oncology and CNS therapeutic areas.
• Agrochemical Research: Serves as a building block for developing new generation herbicides, fungicides, or insecticides with enhanced efficacy.
• Chemical Biology Probe Development: Used in the design and synthesis of molecular probes for studying enzyme function and protein-protein interactions.
• Material Science Research: Potential monomer or additive in the development of specialty polymers with specific optical or electronic properties.
• Academic & Contract Research: Employed in university and CRO settings for methodological development and exploratory synthetic chemistry.

Basic Information

Product Name	4-Chloro-2'-[8-(1,4-Dioxa-8-Azaspiro[4.5]Decyl)Methyl]-3-Fluorobenzophenone
CAS No.	898756-19-9
Molecular Formula	C23H25ClFNO3
Molecular Weight	417.90 g/mol
Synonyms	4-Chloro-3-fluoro-2'-[((1,4-dioxa-8-azaspiro[4.5]dec-8-yl)methyl)]benzophenone; 3-Fluoro-4-chloro-2'-(1,4-dioxa-8-azaspiro[4.5]dec-8-ylmethyl)benzophenone; 898756-19-9; Benzophenone, 4-chloro-3-fluoro-2'-[(1,4-dioxa-8-azaspiro[4.5]dec-8-yl)methyl]-; 4-Chloro-3-fluoro-2'-(8-(1,4-dioxa-8-azaspiro[4.5]decyl)methyl)benzophenone
EINECS	Contact for details

Quality Control

Every batch of 4-Chloro-2'-[8-(1,4-Dioxa-8-Azaspiro[4.5]Decyl)Methyl]-3-Fluorobenzophenone is manufactured under strict quality management systems and undergoes comprehensive analytical characterization to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, which includes data from NMR, HPLC, and mass spectrometry. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring traceability and reliability for critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to minimize exposure to moisture. For long-term storage, consider inert gas purging.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Retention time corresponds to reference standard
Identification (NMR)	Spectrum consistent with structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.