Description

3'-Bromo-2-[8-(1,4-Dioxa-8-Azaspiro[4.5]Decyl)Methyl]Benzophenone is a sophisticated organic building block featuring a benzophenone core functionalized with a bromine substituent and a spirocyclic ketal-protected amine moiety. This compound is of significant value in pharmaceutical research and fine chemical synthesis, where it serves as a key intermediate for constructing complex molecular architectures. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those targeting neurological disorders or acting as protease inhibitors.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Ligand and Catalyst Development: Serves as a starting material for creating complex chelating ligands or organocatalysts due to its spirocyclic amine group.
• Agrochemical Synthesis: Employed in the development of new herbicides or fungicides where the benzophenone skeleton is a key structural element.
• Advanced Material Precursor: Potential use in the synthesis of specialty polymers or organic electronic materials requiring photoactive or charge-transporting units.

Basic Information

Product Name	3'-Bromo-2-[8-(1,4-Dioxa-8-Azaspiro[4.5]Decyl)Methyl]Benzophenone
CAS No.	898755-97-0
Molecular Formula	C21H22BrNO3
Molecular Weight	416.31 g/mol
Synonyms	2-[(8-(1,4-Dioxa-8-azaspiro[4.5]decan-8-yl)methyl]phenyl)(3-bromophenyl)methanone; 3'-Bromo-2-((1,4-dioxa-8-azaspiro[4.5]decan-8-yl)methyl)benzophenone; 898755-97-0; Benzophenone, 3'-bromo-2-[(1,4-dioxa-8-azaspiro[4.5]dec-8-yl)methyl]-; 3-Bromo-2'-(1,4-dioxa-8-azaspiro[4.5]decan-8-ylmethyl)benzophenone
EINECS	Contact for details

Quality Control

Our 3'-Bromo-2-[8-(1,4-Dioxa-8-Azaspiro[4.5]Decyl)Methyl]Benzophenone is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for research and development applications. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP guidelines where applicable, and our quality systems are designed to meet the stringent requirements of pharmaceutical and fine chemical industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.