Description

2'-Azetidinomethyl-2,4-Difluorobenzophenone is a specialized fluorinated benzophenone derivative featuring an azetidine moiety, serving as a high-value pharmaceutical intermediate. Its molecular architecture makes it a critical building block for the synthesis of advanced active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring precise molecular targeting. This compound is essential for research and development chemists and process scale-up teams in the global pharmaceutical and fine chemical industries.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders and anti-infective agents.
• Protease Inhibitor Research: Used in the development of enzyme inhibitors where the difluorobenzophenone scaffold is crucial for binding affinity and metabolic stability.
• Chemical Biology Probes: Employed in the creation of molecular probes for studying enzyme function and signal transduction pathways.
• Material Science Research: Investigated as a monomer or cross-linking agent for developing advanced polymers with specific optical or electronic properties.
• Process Chemistry & Scale-Up: Sourced by contract manufacturing organizations (CMOs) and API manufacturers for process optimization and commercial-scale production.

Basic Information

Product Name	2'-Azetidinomethyl-2,4-Difluorobenzophenone
CAS No.	898755-31-2
Molecular Formula	C17H15F2NO
Molecular Weight	287.31 g/mol
Synonyms	2,4-Difluoro-2'-(azetidin-1-ylmethyl)benzophenone; 1-[(2-Benzoyl-3,5-difluorophenyl)methyl]azetidine; 2'-(Azetidin-1-ylmethyl)-2,4-difluorobenzophenone; (2,4-Difluorophenyl)[2-(azetidin-1-ylmethyl)phenyl]methanone; Azetidine, 1-[[2-benzoyl-3,5-difluorophenyl]methyl]-; 898755-31-2; 2'-Azetidin-1-ylmethyl-2,4-difluorobenzophenone
EINECS	Contact for details

Quality Control

Our 2'-Azetidinomethyl-2,4-Difluorobenzophenone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and stringent control of residual solvents and impurities. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your internal specifications and cGMP guidelines where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.