Description

2',4'-Difluoro-3-(2,6-Dimethylphenyl)Propiophenone is a high-value fluorinated aromatic ketone building block, essential for advanced organic synthesis. Its molecular structure, featuring a propiophenone core with strategically placed fluorine and dimethylphenyl groups, makes it a critical intermediate for creating complex molecules with tailored properties. This compound is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders or requiring enhanced metabolic stability.
• Agrochemical Research: Used in the development of new-generation herbicides, fungicides, and insecticides where the fluorine atoms can improve bioactivity and environmental persistence.
• Material Science Precursor: Serves as a monomer or intermediate for synthesizing specialty polymers, liquid crystals, or organic electronic materials.
• Chemical Synthesis Reagent: Employed in cross-coupling reactions, such as Suzuki or Heck reactions, to introduce complex aryl groups into target molecules.
• Academic & Contract Research: Utilized in university and CRO laboratories for methodological development and exploring new chemical spaces in medicinal chemistry.

Basic Information

Product Name	2',4'-Difluoro-3-(2,6-Dimethylphenyl)Propiophenone
CAS No.	898755-28-7
Molecular Formula	C17H16F2O
Molecular Weight	274.31 g/mol
Synonyms	1-(2,4-Difluorophenyl)-3-(2,6-dimethylphenyl)propan-1-one; 3-(2,6-Dimethylphenyl)-1-(2,4-difluorophenyl)propan-1-one; 2,4-Difluoro-3-(2,6-dimethylphenyl)propiophenone; Propiophenone, 2',4'-difluoro-3-(2,6-dimethylphenyl)-; DFDPP (abbreviation)
EINECS	Contact for details

Quality Control

Every batch of 2',4'-Difluoro-3-(2,6-Dimethylphenyl)Propiophenone is manufactured and tested under strict quality management systems. We provide comprehensive analytical data to ensure the material meets the precise requirements for research and scale-up applications. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents and bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.