Description

4'-Bromo-3-(2,6-Dimethylphenyl)-2'-Fluoropropiophenone is a high-purity, advanced pharmaceutical intermediate characterized by its distinct halogenated aromatic structure. This compound is of significant value in modern organic synthesis, particularly for constructing complex molecular frameworks in medicinal chemistry. It is primarily sought after by research institutions and pharmaceutical manufacturers engaged in the development of novel active pharmaceutical ingredients (APIs) and other fine chemicals.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug candidates, particularly those targeting central nervous system (CNS) disorders or inflammatory pathways.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization processes to develop new therapeutic agents.
• Organic Synthesis Reagent: Serves as a versatile precursor for cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) due to the presence of the bromo substituent.
• Chemical Reference Standard: Employed as an analytical standard in quality control laboratories for method development and validation.
• Agrochemical Research: Potential intermediate in the development of novel crop protection agents and herbicides.
• Material Science Precursor: Can be utilized in the synthesis of specialized ligands for catalysts or functional organic materials.

Basic Information

Product Name	4'-Bromo-3-(2,6-Dimethylphenyl)-2'-Fluoropropiophenone
CAS No.	898755-10-7
Molecular Formula	C17H16BrFO
Molecular Weight	335.21 g/mol
Synonyms	2'-Fluoro-4'-bromo-3-(2,6-dimethylphenyl)propiophenone; 1-(4-Bromo-2-fluorophenyl)-3-(2,6-dimethylphenyl)propan-1-one; 898755-10-7; 4'-Bromo-2'-fluoro-3-(2,6-dimethylphenyl)propiophenone; 3-(2,6-Dimethylphenyl)-1-(4-bromo-2-fluorophenyl)propan-1-one
EINECS	Contact for details

Quality Control

Our 4'-Bromo-3-(2,6-Dimethylphenyl)-2'-Fluoropropiophenone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for critical research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storage under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Heavy Metals	< 10 ppm
Water Content (KF)	< 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.