Description

3-(2,6-Dimethylphenyl)-4'-Trifluoromethylpropiophenone is a specialized organic intermediate featuring a trifluoromethyl-substituted propiophenone core. This compound matters for its role as a critical building block in the synthesis of advanced pharmaceutical and agrochemical molecules, where the trifluoromethyl group is prized for enhancing metabolic stability and lipophilicity. It is primarily needed by R&D chemists and process development scientists in the fine chemical, pharmaceutical, and crop protection industries.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders or inflammatory diseases.
• Agrochemical Synthesis: Serves as a building block for developing novel herbicides, fungicides, or insecticides, leveraging the bioactivity of the trifluoromethyl group.
• Material Science Research: Used in the development of organic electronic materials or liquid crystals due to its specific aromatic and fluorinated structure.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying enzyme mechanisms or protein-ligand interactions.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring this specific fluorinated ketone scaffold.

Basic Information

Product Name	3-(2,6-Dimethylphenyl)-4'-Trifluoromethylpropiophenone
CAS No.	898755-08-3
Molecular Formula	C18H17F3O
Molecular Weight	306.33 g/mol
Synonyms	1-[4-(Trifluoromethyl)phenyl]-3-(2,6-dimethylphenyl)propan-1-one; 4'-Trifluoromethyl-3-(2,6-dimethylphenyl)propiophenone; 3-(2,6-Dimethylphenyl)-1-[4-(trifluoromethyl)phenyl]propan-1-one; Propiophenone, 3-(2,6-dimethylphenyl)-4'-(trifluoromethyl)-; CAS 898755-08-3
EINECS	Contact for details

Quality Control

Our 3-(2,6-Dimethylphenyl)-4'-Trifluoromethylpropiophenone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets stringent specifications for research and development use. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. For long-term storage, consider under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.