Description

3-(2,6-Dimethylphenyl)-2'-Trifluoromethylpropiophenone is a high-purity, advanced pharmaceutical intermediate characterized by its unique aromatic and trifluoromethyl-substituted structure. This compound is critical for the synthesis of complex active pharmaceutical ingredients (APIs), where its specific molecular framework imparts desirable pharmacological properties to the final drug molecule. It is primarily utilized by research institutions and manufacturers in the pharmaceutical and agrochemical industries engaged in the development of new therapeutic agents and specialty chemicals.

Application

• Key Intermediate in Pharmaceutical Synthesis: Serves as a crucial building block for the research and development of novel Active Pharmaceutical Ingredients (APIs), particularly in central nervous system (CNS) and anti-inflammatory drug candidates.
• Agrochemical Research & Development: Used in the synthesis of advanced pesticide and herbicide molecules, leveraging the stability and bioactivity conferred by the trifluoromethyl group.
• Material Science Precursor: Acts as a specialty monomer or precursor in the development of advanced polymers and organic electronic materials.
• Organic Synthesis & Process Chemistry: Employed in academic and industrial laboratories for method development and scale-up studies involving fluorinated ketone chemistry.
• Contract Manufacturing & Custom Synthesis: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of client-specific target molecules under cGMP conditions.

Basic Information

Product Name	3-(2,6-Dimethylphenyl)-2'-Trifluoromethylpropiophenone
CAS No.	898755-04-9
Molecular Formula	C18H17F3O
Molecular Weight	306.32 g/mol
Synonyms	2'-Trifluoromethyl-3-(2,6-dimethylphenyl)propiophenone; 1-[3-(2,6-Dimethylphenyl)-1-oxopropyl]-2-(trifluoromethyl)benzene; 3-(2,6-Dimethylphenyl)-1-[2-(trifluoromethyl)phenyl]propan-1-one; 898755-04-9; Propiophenone, 3-(2,6-dimethylphenyl)-2'-(trifluoromethyl)-
EINECS	Contact for details

Quality Control

Our 3-(2,6-Dimethylphenyl)-2'-Trifluoromethylpropiophenone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specification results. Our quality commitment supports applications requiring high-purity intermediates for pharmaceutical development under cGMP guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.