Description

3-(2,6-Dimethylphenyl)-2'-Fluoropropiophenone is a high-purity fluorinated aromatic ketone building block of significant interest in advanced organic synthesis. Its molecular structure, featuring both a dimethylphenyl group and a fluorophenyl moiety, makes it a valuable precursor for the development of complex pharmaceutical intermediates and fine chemicals. This compound is primarily utilized by research and development chemists and process engineers in the pharmaceutical, agrochemical, and material science industries seeking to introduce specific fluorinated motifs into target molecules.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the research and development of novel active pharmaceutical ingredients (APIs), particularly those requiring fluorinated aromatic systems for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the preparation of advanced herbicide and pesticide candidates, where the fluorine atom can improve biological activity and environmental persistence profiles.
• Ligand and Catalyst Development: Acts as a precursor for creating specialized ligands used in asymmetric catalysis and transition metal complexes.
• Material Science Research: Employed in the synthesis of monomers or additives for advanced polymers and liquid crystals, where fluorination can alter material properties like solubility and thermal stability.
• Chemical Reference Standard: Supplied as a high-purity standard for analytical method development, quality control, and regulatory submissions in chemical manufacturing.

Basic Information

Product Name	3-(2,6-Dimethylphenyl)-2'-Fluoropropiophenone
CAS No.	898755-02-7
Molecular Formula	C17H17FO
Molecular Weight	256.32 g/mol
Synonyms	2'-Fluoro-3-(2,6-dimethylphenyl)propiophenone; 1-(2-Fluorophenyl)-3-(2,6-dimethylphenyl)propan-1-one; 3-(2,6-Dimethylphenyl)-1-(2-fluorophenyl)propan-1-one; α-Ethyl-2',6'-dimethyl-2-fluorobenzhydrol (keto form); Propiophenone, 3-(2,6-dimethylphenyl)-2'-fluoro-; 898755-02-7
EINECS	Contact for details

Quality Control

Our 3-(2,6-Dimethylphenyl)-2'-Fluoropropiophenone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR spectroscopy, to ensure it meets the high standards required for research and industrial synthesis. Certificates of Analysis (COA) detailing all specifications and test results are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (typically 15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.