Description

3-(2,6-Dimethylphenyl)-4'-Fluoropropiophenone is a high-purity fluorinated aromatic ketone intermediate of significant interest in advanced organic synthesis. This compound matters for its role as a critical building block in the development of complex, biologically active molecules, particularly within pharmaceutical research and development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce specific fluorinated aromatic motifs into their target compounds.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), especially those targeting central nervous system (CNS) disorders.
• Agrochemical Research: Used in the development of new-generation herbicides and pesticides where the fluorophenyl group enhances bioavailability and stability.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in asymmetric catalysis and transition metal complexes.
• Material Science Precursor: Employed in the synthesis of monomers or additives for advanced polymers with specific optical or electronic properties.
• Fluorine Chemistry Building Block: Essential for medicinal chemistry programs focused on leveraging the unique properties of fluorine atoms to modulate drug metabolism and binding affinity.

Basic Information

Product Name	3-(2,6-Dimethylphenyl)-4'-Fluoropropiophenone
CAS No.	898754-79-5
Molecular Formula	C17H17FO
Molecular Weight	256.32 g/mol
Synonyms	4'-Fluoro-3-(2,6-dimethylphenyl)propiophenone; 1-(4-Fluorophenyl)-3-(2,6-dimethylphenyl)propan-1-one; 3-(2,6-Dimethylphenyl)-1-(4-fluorophenyl)propan-1-one; Propiophenone, 3-(2,6-dimethylphenyl)-4'-fluoro-; 898754-79-5; 4-Fluoro-3-(2,6-dimethylphenyl)propiophenone; 3-(2,6-Xylyl)-4'-fluoropropiophenone
EINECS	Contact for details

Quality Control

Our 3-(2,6-Dimethylphenyl)-4'-Fluoroprophenone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP guidelines where applicable, ensuring reliability for research and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and bases. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.