Description

4'-Fluoro-3-(2-Thiomethylphenyl)Propiophenone is a specialized fluorinated aromatic ketone derivative featuring a thiomethylphenyl substituent. This compound is a high-value intermediate prized for its unique molecular scaffold, which is critical for constructing complex pharmacologically active molecules. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for use in advanced synthesis programs, including the development of new active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly in medicinal chemistry research for central nervous system (CNS) and metabolic disorder targets.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging its fluorinated aromatic structure for enhanced biological activity and environmental stability.
• Material Science Precursor: Serves as a monomer or precursor for advanced polymers and liquid crystals, where the fluorine atom and sulfur moiety impart specific electronic and physical properties.
• Organic Synthesis Reagent: Employed in academic and industrial laboratories for constructing complex organic molecules, facilitating carbon-carbon and carbon-heteroatom bond-forming reactions.
• Fluorine Chemistry Studies: Acts as a model compound for investigating the effects of fluorine substitution on reaction kinetics and molecular conformation in aromatic systems.

Basic Information

Product Name	4'-Fluoro-3-(2-Thiomethylphenyl)Propiophenone
CAS No.	898754-69-3
Molecular Formula	C16H15FOS
Molecular Weight	274.35 g/mol
Synonyms	1-(4-Fluorophenyl)-3-[2-(methylthio)phenyl]propan-1-one; 3-(2-Methylthiophenyl)-1-(4-fluorophenyl)-1-propanone; 4'-Fluoro-3-(2-methylthiophenyl)propiophenone; 4-Fluoro-3'-(methylthio)propiophenone; Propiophenone, 4'-fluoro-3-(2-(methylthio)phenyl)-; 898754-69-3; 4'-Fluoro-3-(2-thiomethylphenyl)propiophenone
EINECS	Contact for details

Quality Control

Our production of 4'-Fluoro-3-(2-Thiomethylphenyl)Propiophenone adheres to stringent in-process controls and final release testing to ensure batch-to-batch consistency and high purity. We employ advanced analytical techniques including HPLC, GC-MS, and NMR for comprehensive characterization and impurity profiling. A Certificate of Analysis (COA) detailing identity, purity, and related substances is provided with each shipment, supporting compliance with cGMP and ICH Q7 guidelines for active pharmaceutical ingredients (APIs) and advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated place. Recommended long-term storage temperature is 2-8°C. Allow the sealed container to reach ambient temperature before opening to prevent moisture condensation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single unknown impurity ≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.