Description

4'-Chloro-3-(2,5-Dimethylphenyl)-2'-Fluoropropiophenone is a high-purity fluorinated aromatic ketone building block of significant interest in advanced organic synthesis. Its molecular structure, featuring chloro, fluoro, and dimethylphenyl substituents, makes it a versatile intermediate for constructing complex molecules with tailored properties. This compound is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those requiring fluorinated and chlorinated aromatic motifs.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, where its halogenated structure can contribute to biological activity and metabolic stability.
• Material Science Precursor: Serves as a monomer or intermediate in the synthesis of specialty polymers, liquid crystals, and advanced organic electronic materials.
• Chemical Synthesis: A versatile reagent for cross-coupling reactions, carbonyl chemistry, and the introduction of complex aryl groups into target molecules.
• R&D and Process Scaling: Essential for laboratory-scale research, route scouting, and pilot-scale production of specialty fine chemicals.

Basic Information

Product Name	4'-Chloro-3-(2,5-Dimethylphenyl)-2'-Fluoropropiophenone
CAS No.	898753-94-1
Molecular Formula	C17H16ClFO
Molecular Weight	290.76 g/mol
Synonyms	1-(4-Chloro-2-fluorophenyl)-3-(2,5-dimethylphenyl)propan-1-one; 2',4'-Dichloro-3'-(2,5-dimethylphenyl)propiophenone (related isomer); 4-Chloro-2-fluoro-3'-(2,5-dimethylphenyl)propiophenone; Fluorinated Chloro Dimethylphenyl Propiophenone; Aryl Fluoroketone Intermediate; CAS 898753-94-1
EINECS	Contact for details

Quality Control

Every batch of 4'-Chloro-3-(2,5-Dimethylphenyl)-2'-Fluoropropiophenone is manufactured under strict quality management systems. We provide comprehensive analytical data to ensure consistent purity and identity, critical for reproducible research and development outcomes. Certificates of Analysis (COA) detailing purity, impurities, and full spectroscopic characterization (NMR, IR, MS) are supplied with each shipment. Our quality protocols are designed to meet the stringent requirements of GMP and ISO standards for advanced chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents and bases. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.