Description

4'-Bromo-3-(2,5-Dimethylphenyl)-2'-Fluoropropiophenone is a high-purity, fluorinated aromatic ketone building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of complex molecules, particularly in pharmaceutical research and agrochemical discovery. It is needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel active pharmaceutical ingredients (APIs), especially those targeting central nervous system (CNS) disorders and inflammatory diseases.
• Agrochemical Research: Used in the development of new-generation herbicides, fungicides, and insecticides, leveraging the bioactivity of the bromo-fluoro substituted aromatic system.
• Ligand & Catalyst Development: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and transition metal complexes.
• Material Science Precursor: Employed in the synthesis of organic semiconductors, liquid crystals, and advanced polymers where specific fluorine and bromine substitution patterns are required.
• Chemical Biology Probe Synthesis: Utilized to create molecular probes for studying enzyme mechanisms and protein-ligand interactions.

Basic Information

Product Name	4'-Bromo-3-(2,5-Dimethylphenyl)-2'-Fluoropropiophenone
CAS No.	898753-88-3
Molecular Formula	C17H16BrFO
Molecular Weight	335.21 g/mol
Synonyms	2'-Fluoro-4'-bromo-3-(2,5-dimethylphenyl)propiophenone; 1-(4-Bromo-2-fluorophenyl)-3-(2,5-dimethylphenyl)propan-1-one; 3-(2,5-Dimethylphenyl)-1-(4-bromo-2-fluorophenyl)propan-1-one; 4'-Bromo-2'-fluoro-3-(2,5-dimethylphenyl)propiophenone; 898753-88-3; Propiophenone, 4'-bromo-3-(2,5-dimethylphenyl)-2'-fluoro-
EINECS	Contact for details

Quality Control

Our 4'-Bromo-3-(2,5-dimethylphenyl)-2'-fluoropropiophenone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment aligns with cGMP principles for advanced pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This material is moisture-sensitive (hygroscopic) and should be handled under an inert atmosphere for prolonged storage to prevent degradation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.