Description

Ethyl 2,2-Dimethyl-4-Oxo-4-(3,4,5-Trifluorophenyl)Butyrate is a high-purity fluorinated organic ester building block, essential for advanced pharmaceutical and agrochemical synthesis. Its core value lies in its unique trifluorophenyl moiety, which is critical for modulating the biological activity, metabolic stability, and lipophilicity of target molecules. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical industry for creating novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring fluorinated compounds.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders, anti-infectives, and oncology.
• Agrochemical Active Ingredient Precursor: Used in the development of next-generation herbicides and pesticides where the fluorine atoms enhance bioavailability and environmental stability.
• Material Science Research: Serves as a monomer or functional additive in the research of specialty polymers and liquid crystals with tailored electronic properties.
• Chemical Biology Probe Development: Utilized as a building block for creating fluorinated probes and tags used in metabolic pathway studies and imaging.
• Process Chemistry & Scale-Up: Employed in route scouting and optimization for the commercial-scale production of fluorinated fine chemicals.

Basic Information

Item	Details
Product Name	Ethyl 2,2-Dimethyl-4-Oxo-4-(3,4,5-Trifluorophenyl)Butyrate
CAS No.	898753-68-9
Molecular Formula	C14H15F3O3
Molecular Weight	288.26 g/mol
Synonyms	Ethyl 4-(3,4,5-Trifluorophenyl)-2,2-dimethyl-4-oxobutanoate; 4-(3,4,5-Trifluorobenzoyl)-2,2-dimethylbutyric Acid Ethyl Ester; 2,2-Dimethyl-4-oxo-4-(3,4,5-trifluorophenyl)butanoic Acid Ethyl Ester; Butanoic acid, 2,2-dimethyl-4-oxo-4-(3,4,5-trifluorophenyl)-, ethyl ester; 898753-68-9; TFMPB Ethyl Ester
EINECS	Contact for details

Quality Control

Our Ethyl 2,2-Dimethyl-4-Oxo-4-(3,4,5-Trifluorophenyl)Butyrate is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with agreed specifications. Our quality commitment supports applications requiring GMP-grade starting materials and aligns with ICH guidelines for impurity profiling.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to prevent moisture absorption and potential degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.