Description

Ethyl 4-(2,5-Difluorophenyl)-4-Oxobutyrate is a high-purity organic building block and key intermediate in advanced chemical synthesis. This compound is valued for its precise molecular structure, which is critical for constructing complex molecules in regulated industries. It is primarily required by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon in the research and production of novel active pharmaceutical ingredients (APIs), particularly those containing difluorophenyl motifs.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and pesticides where the specific fluorinated structure imparts desired biological activity.
• Material Science Research: Serves as a precursor for specialty polymers and advanced organic materials requiring specific fluorinated aromatic components.
• Organic Synthesis Building Block: Employed in academic and industrial R&D for constructing complex organic molecules via reactions at the ketone and ester functional groups.
• Ligand and Catalyst Development: Utilized in the synthesis of specialized ligands for metal-catalyzed cross-coupling and other transformative reactions.

Basic Information

Product Name	Ethyl 4-(2,5-Difluorophenyl)-4-Oxobutyrate
CAS No.	898753-14-5
Molecular Formula	C12H12F2O3
Molecular Weight	242.22 g/mol
Synonyms	Ethyl 4-(2,5-Difluorobenzoyl)butyrate; 4-(2,5-Difluorophenyl)-4-oxobutanoic Acid Ethyl Ester; Butanoic acid, 4-(2,5-difluorophenyl)-4-oxo-, ethyl ester; Ethyl 4-Oxo-4-(2,5-difluorophenyl)butanoate; 898753-14-5; 4-(2,5-Difluorobenzoyl)butyric Acid Ethyl Ester
EINECS	Contact for details

Quality Control

Our Ethyl 4-(2,5-Difluorophenyl)-4-Oxobutyrate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. Certificates of Analysis (COA) are provided with each shipment, detailing all relevant specifications. We adhere to cGMP principles where applicable to support our clients in regulated markets.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from strong bases and incompatible materials. The container should be kept tightly sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.