Description

Ethyl 7-(2,4-Difluorophenyl)-7-Oxoheptanoate is a high-purity synthetic intermediate characterized by its difluorophenyl and ketoester functional groups. This compound is critical for pharmaceutical research and development, particularly in the synthesis of complex active pharmaceutical ingredients (APIs) where fluorination is used to modulate metabolic stability and bioavailability. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for constructing novel molecular scaffolds.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of fluorinated drug candidates, including potential kinase inhibitors and anti-inflammatory agents.
• Agrochemical Research: Used in the development of novel herbicides and fungicides where the difluorophenyl moiety can enhance biological activity and environmental persistence.
• Material Science Precursor: Serves as a monomer or functionalizing agent in the synthesis of specialty polymers and advanced organic materials.
• Chemical Synthesis: Employed in organic synthesis for chain extension and the introduction of the 7-oxoheptanoate ester group into target molecules.
• Academic & Contract Research: A valuable reagent for methodological studies in fluorination chemistry and medicinal chemistry programs at research institutions and CROs.

Basic Information

Product Name	Ethyl 7-(2,4-Difluorophenyl)-7-Oxoheptanoate
CAS No.	898753-10-1
Molecular Formula	C15H18F2O3
Molecular Weight	284.30 g/mol
Synonyms	Ethyl 7-Oxo-7-(2,4-difluorophenyl)heptanoate; 7-(2,4-Difluorophenyl)-7-oxoheptanoic Acid Ethyl Ester; Heptanoic acid, 7-(2,4-difluorophenyl)-7-oxo-, ethyl ester; 898753-10-1; Ethyl 7-(2,4-Difluorobenzoyl)heptanoate; 2,4-Difluoro-ω-oxobenzeneheptanoic Acid Ethyl Ester
EINECS	Contact for details

Quality Control

Our Ethyl 7-(2,4-Difluorophenyl)-7-Oxoheptanoate is manufactured under strict quality management systems. Each batch is subjected to rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents, strong bases, and sources of ignition. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.