Description

Ethyl 5-(3,4-Difluorophenyl)-5-Oxovalerate is a high-purity, fluorinated keto ester building block of significant interest in advanced organic synthesis. Its molecular structure, featuring a difluorophenyl moiety and a reactive oxovalerate chain, makes it a versatile intermediate for constructing complex pharmacophores. This compound is primarily utilized by research institutions and pharmaceutical development teams engaged in the discovery and process optimization of new active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Research: Used in the development of new herbicides and fungicides, where the difluorophenyl group can enhance biological activity and environmental stability.
• Material Science: Serves as a monomer or cross-linking agent in the creation of specialty polymers with unique fluorinated properties, such as enhanced chemical resistance or modified surface energy.
• Chemical Synthesis: Employed in organic chemistry research for constructing complex molecules via reactions like aldol condensations, reductions, and cyclizations.
• Ligand & Catalyst Development: The keto ester functionality allows for its use in designing novel ligands for asymmetric catalysis or metal-organic frameworks (MOFs).

Basic Information

Product Name	Ethyl 5-(3,4-Difluorophenyl)-5-Oxovalerate
CAS No.	898752-24-4
Molecular Formula	C13H14F2O3
Molecular Weight	256.25 g/mol
Synonyms	5-Oxo-5-(3,4-difluorophenyl)pentanoic acid ethyl ester; Ethyl 5-oxo-5-(3,4-difluorophenyl)valerate; 3,4-Difluoro-γ-oxobenzenepentanoic acid ethyl ester; Ethyl 4-(3,4-difluorobenzoyl)butyrate; 898752-24-4; Ethyl 5-(3,4-difluorobenzoyl)valerate
EINECS	Contact for details

Quality Control

Our production of Ethyl 5-(3,4-Difluorophenyl)-5-Oxovalerate adheres to stringent quality management protocols to ensure batch-to-batch consistency and reliability for your critical research and development projects. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We support compliance with relevant guidelines for advanced pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents and bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.