Description

2-(3-Chloro-5-Fluorophenyl)Ethyl Cyclobutyl Ketone is a high-purity, advanced pharmaceutical intermediate characterized by its unique halogenated aromatic and cyclobutyl ketone structure. This compound is of significant commercial importance for its role in the synthesis of complex active pharmaceutical ingredients (APIs) and other fine chemicals. It is primarily required by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for developing new therapeutic agents and high-value products.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and anti-inflammatory research.
• Agrochemical Synthesis: Used in the development of advanced herbicides and pesticides, leveraging its halogenated phenyl group.
• Organic Synthesis Research: Serves as a versatile precursor for creating complex molecular architectures in academic and industrial R&D laboratories.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands for catalytic processes and material science applications.
• Fine Chemical Production: Integral to the manufacture of specialty chemicals requiring a specific chlorinated and fluorinated phenyl ketone moiety.

Basic Information

Product Name	2-(3-Chloro-5-Fluorophenyl)Ethyl Cyclobutyl Ketone
CAS No.	898751-67-2
Molecular Formula	C13H14ClFO
Molecular Weight	240.70 g/mol
Synonyms	1-[2-(3-Chloro-5-fluorophenyl)ethyl]cyclobutan-1-one; 2-(3-Chloro-5-fluorophenyl)-1-cyclobutylethanone; Cyclobutyl 2-(3-chloro-5-fluorophenyl)ethyl ketone; 3-Chloro-5-fluoro-ω-cyclobutylacetophenone; (3-Chloro-5-fluorophenyl)ethyl cyclobutyl ketone; Ketone, 2-(3-chloro-5-fluorophenyl)ethyl cyclobutyl
EINECS	Contact for details

Quality Control

Every batch of 2-(3-Chloro-5-Fluorophenyl)Ethyl Cyclobutyl Ketone is produced under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, GC, and NMR, to ensure compliance with exacting purity standards suitable for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents and incompatible materials. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.