Description

2-(3-Chloro-5-Fluorophenyl)Ethyl Cyclopropyl Ketone is a high-purity, advanced pharmaceutical intermediate characterized by its specific halogenated aromatic and ketone functional groups. This compound is of critical importance for the synthesis of novel active pharmaceutical ingredients (APIs) and complex organic molecules, where its unique structure serves as a key building block. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating new compounds with targeted biological activity.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and anti-inflammatory therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of new-generation pesticides and herbicides, leveraging its halogenated phenyl moiety.
• Material Science Research: Serves as a precursor for developing specialty polymers and liquid crystals with specific optical or electronic properties.
• Organic Synthesis & Catalysis: Employed in academic and industrial laboratories for methodological studies and as a substrate in cross-coupling reactions.
• Chemical Reference Standard: Used as a high-purity analytical standard for quality control and method validation in analytical laboratories.

Basic Information

Product Name	2-(3-Chloro-5-Fluorophenyl)Ethyl Cyclopropyl Ketone
CAS No.	898751-64-9
Molecular Formula	C12H12ClFO
Molecular Weight	226.67 g/mol
Synonyms	1-Cyclopropyl-2-(3-chloro-5-fluorophenyl)ethan-1-one; 2-(3-Chloro-5-fluorophenyl)-1-cyclopropylethanone; 3-Chloro-5-fluorophenethyl cyclopropyl ketone; Cyclopropyl 3-chloro-5-fluorophenethyl ketone; (3-Chloro-5-fluorophenyl)acetone cyclopropyl ketal (precursor related); Ketone, 2-(3-chloro-5-fluorophenyl)ethyl cyclopropyl; 898751-64-9
EINECS	Contact for details

Quality Control

Every batch of 2-(3-Chloro-5-Fluorophenyl)Ethyl Cyclopropyl Ketone is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency meet the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0% Any single impurity ≤0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.