Description

3-(3-Chloro-5-Fluorophenyl)-2',6'-Dichloropropiophenone is a high-purity, multi-halogenated aromatic ketone building block of significant interest in advanced organic synthesis. Its precise molecular architecture, featuring strategically placed chlorine and fluorine atoms, makes it a critical intermediate for constructing complex pharmacophores and functional materials. This compound is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and anti-inflammatory pathways.
• Agrochemical Synthesis: Serves as a building block for developing new-generation herbicides and fungicides, where the halogenated phenyl group contributes to biological activity and environmental stability.
• Material Science Research: Used in the development of specialty polymers and liquid crystals, where its rigid, halogenated structure can influence material properties.
• Organic Light-Emitting Diode (OLED) Materials: Acts as a synthetic intermediate for electron-transport or host materials in OLED devices.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects requiring complex halogenated intermediates.

Basic Information

Product Name	3-(3-Chloro-5-Fluorophenyl)-2',6'-Dichloropropiophenone
CAS No.	898751-60-5
Molecular Formula	C15H8Cl3FO
Molecular Weight	329.58 g/mol
Synonyms	1-(2,6-Dichlorophenyl)-3-(3-chloro-5-fluorophenyl)propan-1-one; 2',6'-Dichloro-3-(3-chloro-5-fluorophenyl)propiophenone; 3-(3-Chloro-5-fluorophenyl)-1-(2,6-dichlorophenyl)propan-1-one; Propiophenone, 3-(3-chloro-5-fluorophenyl)-2',6'-dichloro-; 898751-60-5
EINECS	Contact for details

Quality Control

Every batch of 3-(3-Chloro-5-Fluorophenyl)-2',6'-Dichloropropiophenone is manufactured under strict quality management protocols. We employ advanced analytical techniques, including HPLC, GC, NMR, and MS, to ensure identity, purity, and consistency meet the exacting standards required for research and process development. A comprehensive Certificate of Analysis (COA) detailing purity, impurity profile, and physical characteristics is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents and bases. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Heavy Metals	< 10 ppm
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.