Description

3-(3-Chloro-5-Fluorophenyl)-2',5'-Dichloropropiophenone is a high-purity, multi-halogenated aromatic ketone building block of significant interest in advanced organic synthesis. Its precise molecular architecture makes it a valuable intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries for the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for central nervous system (CNS) and anti-infective agents.
• Agrochemical Synthesis: Serves as a crucial building block for developing next-generation herbicides, fungicides, and pesticides with enhanced efficacy.
• Material Science Research: Used in the synthesis of specialty polymers, liquid crystals, and organic electronic materials due to its halogenated aromatic core.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying enzyme mechanisms and biological pathways.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific custom synthesis projects.

Basic Information

Product Name	3-(3-Chloro-5-Fluorophenyl)-2',5'-Dichloropropiophenone
CAS No.	898751-32-1
Molecular Formula	C15H8Cl3FO
Molecular Weight	329.58 g/mol
Synonyms	1-(2,5-Dichlorophenyl)-3-(3-chloro-5-fluorophenyl)propan-1-one; 2',5'-Dichloro-3'-(3-chloro-5-fluorobenzoyl)propiophenone; 3-(3-Chloro-5-fluorophenyl)-1-(2,5-dichlorophenyl)propan-1-one; Propiophenone, 3-(3-chloro-5-fluorophenyl)-2',5'-dichloro-; 898751-32-1
EINECS	Contact for details

Quality Control

Our 3-(3-Chloro-5-Fluorophenyl)-2',5'-Dichloropropiophenone is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with agreed specifications. Our quality commitment supports applications requiring high standards, including cGMP for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed to prevent moisture absorption and contamination. Store away from incompatible materials such as strong bases and reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.