Description

3-(3-Chloro-5-Fluorophenyl)-2',3'-Dichloropropiophenone is a high-purity, multi-halogenated aromatic ketone building block of significant interest in advanced organic synthesis. Its complex halogenated structure makes it a critical intermediate for constructing sophisticated molecular architectures, particularly in the pharmaceutical and agrochemical sectors. This compound is essential for research chemists and process development teams working on novel active ingredients, where precise functional group manipulation is required.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of complex drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas requiring halogenated motifs.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and insecticides, where its halogen atoms contribute to biological activity and environmental stability.
• Material Science Research: Serves as a precursor for specialty polymers and liquid crystals, where the introduction of halogenated phenyl groups can modify thermal and optical properties.
• Organic Synthesis Reagent: Employed in cross-coupling reactions (e.g., Suzuki, Stille) and as a substrate for further functionalization, enabling the exploration of new chemical space in academic and industrial R&D.

Basic Information

Product Name	3-(3-Chloro-5-Fluorophenyl)-2',3'-Dichloropropiophenone
CAS No.	898751-24-1
Molecular Formula	C15H8Cl3FO
Molecular Weight	329.58 g/mol
Synonyms	1-(2,3-Dichlorophenyl)-3-(3-chloro-5-fluorophenyl)propan-1-one; 2',3'-Dichloro-3-(3-chloro-5-fluorophenyl)propiophenone; 3-(3-Chloro-5-fluorophenyl)-1-(2,3-dichlorophenyl)propan-1-one; Propiophenone, 3-(3-chloro-5-fluorophenyl)-2',3'-dichloro-; 898751-24-1; C15H8Cl3FO
EINECS	Contact for details

Quality Control

Our production of 3-(3-Chloro-5-Fluorophenyl)-2',3'-Dichloropropiophenone adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is characterized using advanced analytical techniques including HPLC, GC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment, supporting your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents and bases. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.