Description

3'-Chloro-3-(3-Chloro-5-Fluorophenyl)-5'-Fluoropropiophenone is a high-purity fluorinated and chlorinated aromatic ketone intermediate of significant importance in advanced organic synthesis. This compound matters for its role as a critical building block in the development of complex, biologically active molecules, particularly within the pharmaceutical sector. It is primarily needed by research institutions and manufacturers engaged in the synthesis of novel active pharmaceutical ingredients (APIs), agrochemicals, and specialty materials, where its unique halogenated structure enables precise molecular modifications.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas requiring halogenated motifs.
• Agrochemical Research: Used in the development of next-generation herbicides and pesticides, where the fluorine and chlorine atoms can enhance biological activity and environmental stability.
• Material Science: Serves as a monomer or building block for creating specialty polymers and liquid crystals with specific optical or electronic properties.
• Chemical Synthesis: Employed in cross-coupling reactions, such as Suzuki or Heck reactions, to construct complex biaryl systems common in many functional molecules.
• Academic & Contract Research: Utilized in university and CRO (Contract Research Organization) laboratories for methodological development and exploration of new chemical spaces.

Basic Information

Product Name	3'-Chloro-3-(3-Chloro-5-Fluorophenyl)-5'-Fluoropropiophenone
CAS No.	898751-16-1
Molecular Formula	C15H8Cl2F2O
Molecular Weight	313.13 g/mol
Synonyms	1-[3-Chloro-5-fluorophenyl]-3-(3-chloro-5-fluorophenyl)propan-1-one; 3-Chloro-3'-(3-chloro-5-fluorophenyl)-5'-fluoropropiophenone; 3',5'-Dichloro-3,5-difluoropropiophenone (ambiguous); Propiophenone, 3'-chloro-3-(3-chloro-5-fluorophenyl)-5'-fluoro-; CAS 898751-16-1
EINECS	Contact for details

Quality Control

Our 3'-Chloro-3-(3-Chloro-5-Fluorophenyl)-5'-Fluoropropiophenone is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP standards where applicable, ensuring reliability for your most critical R&D and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be light-sensitive; prolonged exposure to light should be avoided. Keep away from strong oxidizing agents and bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.