Description

3-(3-Chloro-5-Fluorophenyl)-3',5'-Dimethylpropiophenone is a high-purity, advanced pharmaceutical intermediate (API intermediate) characterized by its specific halogenated aromatic structure. This compound is of critical importance for the synthesis of complex active pharmaceutical ingredients (APIs), where its defined molecular framework serves as a key building block. It is primarily needed by research institutions and manufacturers in the pharmaceutical and agrochemical industries engaged in developing new therapeutic agents and specialty chemicals.

Application

• Pharmaceutical Intermediate: A crucial building block in the multi-step synthesis of novel drug candidates, particularly in central nervous system (CNS) and oncology research.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, leveraging its halogenated phenyl group for bioactivity.
• Chemical Research & Development: Serves as a versatile precursor in organic synthesis for creating complex molecules with specific fluorinated and chlorinated motifs.
• Material Science: Potential use in the synthesis of specialty polymers and liquid crystals where thermal stability and specific electronic properties are required.

Basic Information

Product Name	3-(3-Chloro-5-Fluorophenyl)-3',5'-Dimethylpropiophenone
CAS No.	898750-79-3
Molecular Formula	C17H16ClFO
Molecular Weight	290.76 g/mol
Synonyms	1-(3-Chloro-5-fluorophenyl)-3-(3,5-dimethylphenyl)propan-1-one; 3',5'-Dimethyl-3-(3-chloro-5-fluorophenyl)propiophenone; 3-(3-Chloro-5-fluorophenyl)-1-(3,5-dimethylphenyl)propan-1-one; Propiophenone, 3-(3-chloro-5-fluorophenyl)-3',5'-dimethyl-; 898750-79-3; CAS 898750-79-3
EINECS	Contact for details

Quality Control

Our 3-(3-Chloro-5-Fluorophenyl)-3',5'-Dimethylpropiophenone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing purity, impurity profiles, and physical characteristics are provided with every shipment to guarantee supply reliability and batch-to-batch consistency for your critical R&D and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). The container should be kept tightly sealed in a dry environment to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.