Description

3-(3-Chloro-5-Fluorophenyl)-2',4'-Dimethylpropiophenone is a high-purity, advanced pharmaceutical intermediate characterized by its specific halogenated aromatic structure. This compound is critical for the synthesis of complex active pharmaceutical ingredients (APIs), where its defined molecular framework serves as a key building block. It is primarily required by R&D laboratories and production facilities in the pharmaceutical and agrochemical industries for developing new therapeutic and crop protection agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and anti-inflammatory research.
• Agrochemical Synthesis: Used in the development of advanced herbicides and pesticides, leveraging its halogenated phenyl group for bioactivity.
• Chemical Research & Development: Serves as a versatile scaffold for medicinal chemistry, enabling structure-activity relationship (SAR) studies.
• Material Science: Potential use in the synthesis of specialty polymers and liquid crystals due to its rigid, substituted aromatic core.
• Reference Standard: Employed as an analytical standard in quality control laboratories for method development and validation.

Basic Information

Item	Details
Product Name	3-(3-Chloro-5-Fluorophenyl)-2',4'-Dimethylpropiophenone
CAS No.	898750-67-9
Molecular Formula	C17H16ClFO
Molecular Weight	290.76 g/mol
Synonyms	1-(3-Chloro-5-fluorophenyl)-3-(2,4-dimethylphenyl)propan-1-one; 3-(3-Chloro-5-fluorophenyl)-1-(2,4-dimethylphenyl)propan-1-one; 2',4'-Dimethyl-3-(3-chloro-5-fluorophenyl)propiophenone; Propiophenone, 3-(3-chloro-5-fluorophenyl)-2',4'-dimethyl-; 898750-67-9
EINECS	Contact for details

Quality Control

Our 3-(3-Chloro-5-Fluorophenyl)-2',4'-Dimethylpropiophenone is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, confirming compliance with customer specifications and industry best practices.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.