Description

3'-Bromo-3-(3-Chloro-5-Fluorophenyl)Propiophenone is a high-purity, halogenated aromatic ketone intermediate of significant importance in advanced organic synthesis. This compound is valued for its precise molecular architecture, which serves as a critical building block for constructing complex pharmacologically active molecules. It is primarily needed by research institutions and manufacturers in the pharmaceutical and agrochemical industries for the development of new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel drug candidates, particularly in medicinal chemistry programs.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, leveraging its halogenated phenyl group for bioactivity.
• Material Science Research: Serves as a precursor for the synthesis of specialty polymers and liquid crystals with specific electronic or optical properties.
• Organic Synthesis Building Block: Employed in cross-coupling reactions (e.g., Suzuki, Stille) and other catalytic transformations to create complex molecular structures.
• Chemical Reference Standard: Used as an analytical standard in quality control laboratories for method development and validation.

Basic Information

Product Name	3'-Bromo-3-(3-Chloro-5-Fluorophenyl)Propiophenone
CAS No.	898750-46-4
Molecular Formula	C15H11BrClFO
Molecular Weight	356.60 g/mol
Synonyms	1-(3-Bromophenyl)-3-(3-chloro-5-fluorophenyl)propan-1-one; 3'-Bromo-3-(3-chloro-5-fluorophenyl)-1-phenylpropan-1-one; 3-(3-Chloro-5-fluorophenyl)-1-(3-bromophenyl)propan-1-one; Propiophenone, 3'-bromo-3-(3-chloro-5-fluorophenyl)-; 898750-46-4; 3-Bromo-3'-(3-chloro-5-fluorophenyl)propiophenone
EINECS	Contact for details

Quality Control

Our 3'-Bromo-3-(3-Chloro-5-Fluorophenyl)Propiophenone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical R&D and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.