Description

4'-Carboethoxy-3-(3-Chloro-5-Fluorophenyl)Propiophenone is a high-purity, advanced pharmaceutical intermediate critical for the synthesis of complex active pharmaceutical ingredients (APIs). This compound is valued for its precise molecular structure, which serves as a key building block in modern medicinal chemistry. It is primarily required by R&D laboratories and production facilities in the pharmaceutical and fine chemical industries engaged in developing new therapeutic agents.

Application

• Pharmaceutical Intermediate: A crucial precursor in the multi-step synthesis of novel drug candidates, particularly in central nervous system (CNS) and metabolic disorder research.
• API Synthesis: Used as a building block for constructing complex molecular architectures in Active Pharmaceutical Ingredient (API) manufacturing.
• Medicinal Chemistry R&D: Employed in research and development for structure-activity relationship (SAR) studies and lead optimization processes.
• Fine Chemical Production: Serves as a specialized intermediate in the production of other high-value, fluorinated and chlorinated fine chemicals.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects under cGMP guidelines.

Basic Information

Product Name	4'-Carboethoxy-3-(3-Chloro-5-Fluorophenyl)Propiophenone
CAS No.	898750-37-3
Molecular Formula	C18H16ClFO3
Molecular Weight	334.77 g/mol
Synonyms	Ethyl 4-[3-(3-chloro-5-fluorophenyl)-3-oxopropyl]benzoate; 3-(3-Chloro-5-fluorophenyl)-1-(4-(ethoxycarbonyl)phenyl)propan-1-one; 1-[4-(Ethoxycarbonyl)phenyl]-3-(3-chloro-5-fluorophenyl)-1-propanone; Propiophenone, 4'-carboethoxy-3-(3-chloro-5-fluorophenyl)-; 898750-37-3; 4'-(Ethoxycarbonyl)-3-(3-chloro-5-fluorophenyl)propiophenone
EINECS	Contact for details

Quality Control

Our 4'-Carboethoxy-3-(3-Chloro-5-Fluorophenyl)Propiophenone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) are available for every shipment, confirming compliance with client specifications and industry standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong oxidizing agents, strong bases, and strong acids. The container must be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.